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Recently denosumab demonstrated a significant
2019-05-13
Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R
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In summary current evidence suggests that bone targeted agen
2019-05-13
In summary, current evidence suggests that bone-targeted agents reduce morbidity from metastatic disease to bone, and potentially improve quality of life in patients with metastatic breast cancer. As there are costs and potential adverse effects associated with these agents, care should be taken in
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br Bisphosphonate use and breast cancer
2019-05-13
Bisphosphonate use and breast cancer risk BPs are commonly used in the management of postmenopausal osteoporosis. They consist of two phosphate groups, which give them a high affinity to bone. They attach to bone at exposed calcium hydroxyapatite binding sites, which are most accessible at sites
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Osteoporosis was defined as BMD standard deviations or more
2019-05-13
Osteoporosis was defined as BMD 2.5 standard deviations or more below the reference range mean for young adults. Osteopaenia being those with a BMD between 1 and 2.5 standard deviations below the young adult mean [7]. Lumbar spine (L2-L4) and femoral neck BMD was quantified with Lunar DPX-L (Lunar,
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A previous study reported that
2019-05-13
A previous study reported that patients with early AF recurrences were significantly less likely to have long-term freedom from recurrent AF than patients without early recurrences [3]. In the present study, landiolol administration tended to improve the mid-term prognosis compared to placebo. In a
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It is well known that the precipitation of solid
2019-05-13
It is well-known that the precipitation of solid cholesterol monohydrate crystals from supersaturated bile is the first irreversible physical-chemical step in gallstone formation. To study the characteristics, metastable intermediates, and kinetics in the phase transitions of bile, a series of phase
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Asimismo el texto convoca a cuestionar muchos de los
2019-05-13
Asimismo, el texto convoca tryptophan hydroxylase cuestionar muchos de los mitos sobre la guerra civil en Guatemala. No fue durante los años setenta que los revolucionarios guatemaltecos volcaron su mirada sobre el componente indígena como parte de las fuerzas insurgentes, tampoco fue en los ochenta
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Resulta importante resaltar el surgimiento de nuevos patrone
2019-05-13
Resulta importante resaltar el surgimiento de nuevos patrones de lectura e interpretación de los escenarios políticos en Latinoamérica, porque ello explica su desplazamiento en los modos de leer que hasta 1960 habían caracterizado sus ensayos. Estos descubrimientos propiciados por la Revolución pusi
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oxycodone hydrochloride cost A review by Keung and colleague
2019-05-13
A 2002 review by Keung and colleagues summarized cases of hematologic malignancy in patients with KS reported between 1961 and 2002 [3]. They described 12 cases of AML in KS in the literature during that time period. Based on the review of the current literature, we found approximately 10 additional
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Results from the present study
2019-05-13
Results from the present study also showed improvement in timelines for measles immunisation, which is scheduled at 9 months of age, almost a gap of 6 months from the last vaccine according to EPI schedule for LMICs. Although the major focus up until now has been on reminder messages, the impact of
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Successful and safe catheter ablation is facilitated by an a
2019-05-13
Successful and safe catheter ablation is facilitated by an appreciation for anatomical particularities and surgical details. Morphological analysis of clinically documented VT is also important. In these patients, VT usually shows a left bundle branch block-like QRS morphology and inferior frontal p
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br Discussion Variant angina was described
2019-05-13
Discussion Variant histamine-1 receptor antagonist was described by Prinzmetal et al. in 1959 [1]. It can involve serious arrhythmias such as ventricular tachycardia, ventricular fibrillation, and atrioventricular block, and patients are particularly susceptible to sudden cardiac death in such ca
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Early recognition of ICD lead malfunction is desirable to pr
2019-05-13
Early recognition of ICD lead malfunction is desirable to prevent the life-threatening consequences of lead failure. Recent reports indicate that the majority of patients with ICD lead failure experience inappropriate ICD therapies, often as the presenting problem [4,6]. Regular device interrogation
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br Case report The patient then achieved disease
2019-05-10
Case report The patient then achieved disease-free status as noted in a series of routine image studies during regular follow-up at our oncology clinic. In November 2011, she presented due to hematuria for several days. Diagnostic cystoscopy showed a mass lesion on the urinary bladder. Whole body
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br Case report A year old female presented with splenomegaly
2019-05-10
Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (smo inhibitor of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubicin; vincis
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