• Current ASCO recommendations suggest initiating bisphosphona

  2019-05-15

  

  Current ASCO recommendations suggest initiating bisphosphonate therapy in myeloma when there is evidence of bone involvement [124]. The optimal duration and frequency of bisphosphonate therapy for myeloma are not well understood and are currently being studied. All randomized, placebo-controlled tri

• br Methods br Results br Discussion One of the hallmarks

  2019-05-15

  

  Methods Results Discussion One of the hallmarks of cancer is the ability of cancer γ-Secretase inhibitor IX to evade apoptosis. Inhibition of apoptosis not only enhances the survival of cancer cells but also facilitates their escape from chemotherapy [5]. Therefore, apoptosis regulatory mec

• br Discussion Wellens reported an association

  2019-05-15

  

  Discussion Wellens [1] reported an association between accessory pathways characterized by anterograde decremental conduction and the description of nodoventricular connections by Mahaim [2]. Consequently, these accessory pathways were erroneously referred to as “Mahaim pathways.” McClelland et a

• Two years later he complained

  2019-05-15

  

  Two years later, he complained of two ICD shocks during a dance party. The possibility of lead fracture or electromagnetic interference was completely excluded after several examinations. Intracardiac electrograms showed that all delivered shocks were inappropriate therapies due to TWOS. The R wave

• Jes s estigmatiz en su predicaci n la

  2019-05-14

  

  “Jesús estigmatizó en su predicación la injusticia social de su tiempo” y lo hizo sin compasión, decía Cullmann. “Jesús anuncia que, a la luz del Reino que ha de venir, la diferencia entre ricos y pobres es contraria a la voluntad divina. Ese juicio sobre el orden social presente es, de suyo, revolu

• One of the unheralded developments

  2019-05-14

  

  One of the unheralded developments in global health is the welcome increase in the number of older people (ie, aged 60 or 65 years and older) in low-income and middle-income countries. In parallel with the gains from this longevity dividend, ageing presents particular challenges to health services.

• candesartan cilexetil br Discussion The excimer laser genera

  2019-05-14

  

  Discussion The excimer laser generator and the laser sheath allow for the extraction of leads while freeing them from the site of adhesion by making use of photoablation induced by the energy of ultraviolet rays. Since its approval in 1997 by the US Food and Drug Administration, the use of excim

• br Conclusion br Conflict of interest br Case report A

  2019-05-14

  

  Conclusion Conflict of interest Case report A 65-year-old woman with permanent atrial fibrillation was admitted with diastolic 17 alpha hydroxylase failure (HF) secondary to rapid ventricular response. She had undergone single chamber pacemaker implantation (Boston Scientific Ingenio SR) t

• Hasta el tercer acto cuando Licurgo se

  2019-05-14

  

  Hasta el tercer acto, cuando Licurgo se casa y vuelve pak4 la racionalidad, presenta al Rey una serie de leyes, quien, sin conocerlas, le pregunta si desea hacerlas públicas, pero, desde otra óptica, Licurgo responde: Son, pues, el Rey y el Reino quienes deben acordar las leyes, para evitar caer en

• El intelectual chileno Felipe Rivas San Mart

  2019-05-13

  

  El intelectual chileno, Felipe Rivas San Martín, advertido de las críticas TAK-875 la globalización del término, describe dos modos en los que la teoría queer se usa en Latinoamérica. Por un lado: Reflexiones finales En la época pos-Stonewall el mercado ha aceptado ciertas identidades sexuales c

• Bafetinib The study reported high rates of

  2019-05-13

  

  The study reported high rates of antimicrobial resistance and also reminds us of the paucity of new drugs to treat such infections, especially in neonates, as well as the paucity of data on antimicrobial pharmacokinetics in this population. Observational and interventional multicentre studies are ne

• In our study ES SCLC patients

  2019-05-13

  

  In our study, ES-SCLC patients in the CIT group were on average older than those in the control group. However, the multivariate analysis showed that age had no effect on the prognosis of these patients. Therefore, age was no a confounding factor, although it has been reported that effector cell fun

• Recently denosumab demonstrated a significant

  2019-05-13

  

  Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R

• In summary current evidence suggests that bone targeted agen

  2019-05-13

  

  In summary, current evidence suggests that bone-targeted agents reduce morbidity from metastatic disease to bone, and potentially improve quality of life in patients with metastatic breast cancer. As there are costs and potential adverse effects associated with these agents, care should be taken in

• br Bisphosphonate use and breast cancer

  2019-05-13

  

  Bisphosphonate use and breast cancer risk BPs are commonly used in the management of postmenopausal osteoporosis. They consist of two phosphate groups, which give them a high affinity to bone. They attach to bone at exposed calcium hydroxyapatite binding sites, which are most accessible at sites

15934 records 1049/1063 page Previous Next First page 上5页 10461047104810491050 下5页 Last page