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br Discussion Prehabilitation is a program to enhance functi
2019-05-05
Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and
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CT analysis of tumour bearing bones showed
2019-05-05
μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic SL-327 caused sustained bone effects throughout the experim
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br Conflict of interest statement
2019-05-05
Conflict of interest statement Acknowledgments Funded by the Division of Medical Oncology at Princess Margaret Hospital, Toronto, Canada. No pharmaceutical company funding was received. The authors acknowledge the roles of Esther Lee and Tazmin Usmani in trial coordination and Dr. Ranjeeta Mal
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Introduction Benign tumours of the bone consist of
2019-05-05
Introduction Benign tumours of the bone consist of a wide variety of different neoplasms. These tumours vary in terms of incidence, clinical presentation and require a diverse array of therapeutic options. The incidence of benign bone tumours is debated due to their often asymptomatic presentation
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It is noted that in this study
2019-05-05
It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation
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It must be noted that modern physical techniques for
2019-05-05
It must be noted that modern physical techniques for structural analysis of steroids were not available to these early talented scientists that time. It was a challenging task for these early scientists to precisely identify the chemical structures of cholesterol and bile acids. However, the develop
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In the context of our present work that uses total
2019-05-05
In the context of our present work that uses total community treatment with azithromycin for yaws eradication, we would support an empirical approach to treatment. Azithromycin is effective for treatment of both and , so our mass treatment should be effective for both causes of skin ulcer. isolate
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UMI-77 Leptin synthesized in adipocytes is a regulator of
2019-05-05
Leptin, synthesized in adipocytes, is a regulator of fat metabolism and reproduction [7]. The levels of leptin correlate with body fat mass and show a wide variation in individuals. In the bone marrow microenvironment, the leptin secreting adipocytes occupy a significant part [8]. Leptin stimulates
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In conclusion we observed that the rate
2019-05-04
In conclusion, we observed that the rate of carbapenem-resistant A. baumannii was high among burn patients. In addition, the most effective drugs against A. baumannii in vitro were colistin and polymyxin B. Since resistant isolates only had blaOXA-23-like and blaOXA-24-like, it seems that carbapenem
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Upon examining his previous hospital records from years prio
2019-05-04
Upon examining his previous hospital records from 4 years prior, we found that he was diagnosed with acute heart failure at the second hospitalization 1 week after catheter ablation for atrial fibrillation. His symptoms and chest radiographic findings had improved by standard therapy for heart failu
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Discussion Mantle cell lymphoma is
2019-05-04
Discussion Mantle cell lymphoma is a distinct type of mature B-cell neoplasm that accounts for approximately 3–10% of non-Hodgkin\'s lymphoma. It is referred to several aliases, such as lymphocytic lymphoma of intermediate differentiation, mantle zone lymphoma, centrocytic lymphoma. Diffusion of no
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Cell adhesion to extracellular matrix requires
2019-05-04
Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp
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mps1 ICG which simply and non invasively measures
2019-05-04
ICG, which simply and non-invasively measures changes in thoracic impedance generated by fluctuating blood volumes during the cardiac cycle, allows for the calculation of stroke volume, CO, and other derived parameters[17]. In recent years, the accuracy of ICG has been greatly improved by the advent
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br Materials and methods This study included WCD patients
2019-05-04
Materials and methods This study included WCD patients with high risk of SCD but did not meet the eligibility criteria for immediate Dynasore cost of an implantable cardioverter defibrillator (ICD). Current guidelines endorse indications for WCD therapy [5]. Patients with low left ventricular ej
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soluble guanylate cyclase The investigators suggest use of
2019-05-04
The investigators suggest use of doxycycline, which is effective for both diseases, as a possible empirical treatment at the primary level of care. Because the consequences of an untreated true case of rickettsiosis or leptospirosis are much greater than are those of unnecessary treatment, Mayxay an
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