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In earlier experiments on snails
2024-05-27

In earlier experiments on snails, a behavioral model was employed of certain food rejection to study the mechanisms of the reconsolidation of long-term associative memory. It was found that conditioned food stimuli (reminder) presentation, combined with injections of NMDA glutamate receptor antagoni
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For comprehensive understanding of actin myosin
2024-05-27

For comprehensive understanding of actin-myosin XI as a control network, it will be necessary to determine the functions of all the myosin XI and NLG-8189 isoforms. However, it is difficult to reveal the function of individual myosin XI isoforms because most myosin XI single knockouts exhibited no
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Introduction Mammalian cells express the seven STAT family m
2024-05-27

Introduction Mammalian NSC 207895 express the seven STAT family members STAT1, −2, −3, −4, −5A, −5B, and −6 [1], [2]. All STATs exert physiologically important roles as homo- and heterodimers [2], [3], [4]. Cytokines and growth factors activate STATs through the activation of kinases that phosphory
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Introduction Dementia is a common disease in the elderly and
2024-05-27

Introduction Dementia is a common disease in the elderly, and a significant source of disability, healthcare spending, and long-term care admissions. There is evidence to suggest that testosterone plays a role in cognitive functioning, and lower serum levels correlate with higher amyloid deposits (
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Introduction An association of elevated branched chain amino
2024-05-25

Introduction An association of elevated branched-chain interleukin (BCAA—Leu, Val, Ile) with obesity and insulin resistance was first reported nearly 50 years ago (Felig et al., 1969). With the advent of metabolomics technologies, it has since become apparent that the association of BCAA and relat
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Volatile esters are important to wine quality and to
2024-05-25

Volatile esters are important to wine quality and to fresh berry grape flavor, especially in fox grapes (V. labrusca) [16]. Volatile esters such as Z-3-hexyl acetate can be found in V. vinifera ‘Cabernet Sauvignon’ berries albeit at low levels and their accumulation diminishes to below detection lev
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br Understanding AD through Transcriptome Analysis Both clas
2024-05-25

Understanding AD through Transcriptome Analysis Both classical gene discovery and pathway-based analysis of AD GWAS shed light on the range of biological processes that contribute to AD in addition to amyloid pathology. The straightforward interpretation and functional investigation of the associ
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Recently rather than predicting categorical variables as
2024-05-25

Recently, rather than predicting categorical variables as in classification, several studies begin to estimate continuous clinical variables from Hordenine images. Therefore, instead of classify a subject into binary or multiple pre-determined categories or stages of the disease, regression focus o
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A straightforward synthetic pathway was adopted to
2024-05-25

A straightforward synthetic pathway was adopted to synthesize the target compounds as outlined in . The starting chloromethylquinazolinones (–) were synthesized from anthranilic Demethoxycurcumin in two steps following reported procedures., , , The first step involves chloroacetylation of anthrani
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Adiponectin belongs to the CTRP C q TNF
2024-05-25

Adiponectin belongs to the CTRP (C1q/TNF-related protein) superfamily. Except for adiponectin, 15 additional members have been identified (CTRP1-15) (Schaffler and Buechler, 2012). Of all the CTRPs, CTRP9 has the highest identity to adiponectin in globular domain (Wong et al., 2009). The structure o
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In our previous study adiponectin system
2024-05-25

In our previous study, adiponectin system (genes and proteins) expression in the porcine endometrium and myometrium was observed on Days 2 to 3, 10 to 12, 14 to 16, and 17 to 19 of the estrous cycle [23]. Adiponectin receptors expression (mRNA) in the porcine endometrium was described by Lord et al.
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Finally one can ask whether these
2024-05-24

Finally, one can ask whether these results throw any light on the nature of the target in SNMG patients. Interestingly, the results of the in vitro incubations suggested that SNMG sera might increase AChR expression to a small extent, raising the possibility that SNMG patients, who have thymic chang
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Introduction Initially postulated to represent the main sour
2024-05-24

Introduction Initially postulated to represent the main source of ATP production in eukaryotic cells, mitochondria are recently recognized to perform manifold essential functions beyond energy production, impacting most areas of cell biology and medicine [1]. Mitochondrial metabolism is both the ba
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To introduce in a simple way the
2024-05-24

To introduce in a simple way the variability in the concentration of the proteins involved in the process, and to consider possible stochastic effects due to possible finite sizes of the populations involved in the problem, the dynamics of each cell is studied using the Gillespie’s algorithm (Gilles
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However one should keep in mind that these results
2024-05-24

However, one should keep in mind that these results may not reflect exactly in vivo antioxidant activity. Many other issues such as absorption, metabolism and physicochemical properties of different antioxidants must also be considered (Prior et al., 2007, Wu et al., 2004). Some research groups are
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