• There are two ways to transport FFAs

  2024-02-29

  

  There are two ways to transport FFAs into cells. First by passive diffusion. Second as the putative long-chain fatty Biotin Hydrazide transporters are proposed, CD36 the plasma membrane-associated fatty acid-binding protein (FABPpm) and fatty acid transport proteins (FATP) [11], where CD36 is respo

• br Hyperadiponectinemia in disease conditions Other evidence

  2024-02-29

  

  Hyperadiponectinemia in disease conditions Other evidence indicates that hyperadiponectinemia does not necessarily always imply a healthy outcome. Indeed, a recent study suggested that hyperadiponectinemia occurs in various diseases. Given that the risk for AD and vascular dementia is increased i

• Multiple ASD susceptibility genes converge on cellular pathw

  2024-02-28

  

  Multiple ASD susceptibility genes converge on cellular pathways that intersect at the postsynaptic site of glutamatergic synapses (Bourgeron, 2015; Peca & Feng, 2012), the development and maturation of synaptic contacts (Gilman et al., 2011) or synaptic transmission (Li et al., 2014). The majority o

• br ARIs in the prevention

  2024-02-28

  

  5ARIs in the prevention of prostate cancer Prostate cancer continues to be a leading cause of male deaths worldwide. In 2009, it was estimated there would be 192,280 new cases of prostate cancer with a predicted 27,360 deaths [25]. Because androgens, and specifically DHT, play a large role in bot

• Wnt-C59 Whereas more research is needed to identify the

  2024-02-28

  

  Whereas more research is needed to identify the precise mechanism by which FIN exerts its antidyskinetic effect, the Wnt-C59 that it can negatively modulate dopaminergic transmission is also supported by our previous findings. Indeed, we have previously shown that FIN completely reversed the behavi

• Drug resistance development often involves

  2024-02-28

  

  Drug resistance development often involves structurally un-related drugs and, specifically both conventional and targeted agents. IGROV-1/Pt1 SGI-1776 are characterized by resistance to cisplatin and reduced sensitivity to inhibitors of EGF-R and MEK, the up-stream activator of ERK1/2, associated w

• br Conclusion br List of abbreviations br Acknowledgment

  2024-02-28

  

  Conclusion List of abbreviations Acknowledgment The studies performed by our laboratory and presented in this review were supported by the Ministry of Education, Culture, Sports, Science and Technology of Japan, (KAKENHI 17590618 [to H.I.] and KAKENHI 22249017 [to Y.Y.]), and the Japanese S

• br Aromatase the key enzyme for estrogen formation

  2024-02-28

  

  Aromatase: the key enzyme for estrogen formation in adipose tissue Estrogens are synthesized from androgens by aromatase, a member of the cytochrome P450 superfamily, which is the rate-limiting enzyme in estrogen biosynthesis (Santen et al, 2009, Simpson et al, 1994). At the cellular level, aroma

• The objectives of this study were to investigate

  2024-02-28

  

  The objectives of this study were to investigate 1) the mRNA and protein expression of apelin and APJ in porcine ovarian follicles of different sizes, and their immunolocalization and concentrations in follicular fluid and ovarian follicle, and 2) the direct effect of recombinant human apelin-13 on

• Recently dairy proteins obtained from

  2024-02-28

  

  Recently, dairy proteins obtained from whey have received considerable attention for their antioxidant bioactivity (Bayram et al., 2008; Haraguchi et al., 2011; Zhang et al., 2012). Bovine whey proteins (WP) are widely used in various foods for their nutritional, health-promoting, and functional val

• It has been proposed that

  2024-02-28

  

  It has been proposed that angiotensin II (Ang II) may upregulate COX-2 expression and the subsequent vasoconstrictor prostanoids production through the activation of AT-1 receptors in vascular smooth muscle cells (Hu et al., 2002). Additionally, this peptide is also able to stimulate the generation

• br Adenosine receptors and innate immunity

  2024-02-27

  

  Adenosine receptors and innate immunity Monocytes and macrophages. All four adenosine receptor subtypes are expressed on monocytes and macrophages, and their levels and function undergo significant changes during the maturation of macrophages from monocytes. Indeed, quiescent monocytes are charac

• By applying each external load to the

  2024-02-27

  

  By applying each external load to the G-actin molecule, and measuring the elongation of the molecule, we computed force-displacement curves. The force versus displacement curve can be used to evaluate the tensile stiffness of the G-actin from a linear regression analysis. Followed by statistical ana

• br Methods br Results and discussion br Conclusions

  2024-02-27

  

  Methods Results and discussion Conclusions Acknowledgements The authors thank Dr. Francois Alhenc-Gelas (then INSERM U367, Paris, France), who kindly provided the plasmid for truncated soluble recombinant human ACE – WTΔ, Dr. Elena Arablinskaya (Institute of Phtiziopulmonology, Moscow, R

• br ARIs in the prevention of prostate cancer Prostate cancer

  2024-02-27

  

  5ARIs in the prevention of prostate cancer Prostate cancer continues to be a leading cause of male deaths worldwide. In 2009, it was estimated there would be 192,280 new cases of prostate cancer with a predicted 27,360 deaths [25]. Because androgens, and specifically DHT, play a large role in bot

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