• On the other hand oxygen concentration in

  2023-08-07

  

  On the other hand, oxygen concentration in tumor tissue also depends on its consumption rate by tumor cells, which decrease will also lead to alleviation of hypoxia. This fact is not taken into account in the majority of studies on the topic, although it is well-known that antiangiogenic therapy doe

• The lack of benefit in terms of overall

  2023-08-07

  

  The lack of benefit in terms of overall survival for antiangiogenic treatment was similar when antiangiogenic drug was used both as first and second-line therapy, and both in association with cytotoxic treatment or alone. Noteworthy, a trend for an inferior outcome was observed in the group of patie

• aldose reductase br Study approval br Author contributions b

  2023-08-07

  

  Study approval Author contributions Conflicts of interest Acknowledgements This work was supported by grants of the Youth Backbone Program (to Jianming Ying) of Cancer Hospital, CAMS, Beijing, Beijing Hope Run Special Fund of Cancer Foundation of China (LC2015A06) and the National Natura

• In this study using pure enzyme preparations of human placen

  2023-08-07

  

  In this study, using pure enzyme preparations of human placental recombinant AR (hAR) and of AR isolated from bovine lens (bAR), which behave as Michaelis AZ505 ditrifluoroacetate with glyceraldehyde as substrate, is shown that an apparent negative cooperativity action for glucose still occurs. We

• In our previous study adiponectin system genes and

  2023-08-07

  

  In our previous study, adiponectin system (genes and proteins) expression in the porcine endometrium and myometrium was observed on Days 2 to 3, 10 to 12, 14 to 16, and 17 to 19 of the estrous cycle [23]. Adiponectin receptors expression (mRNA) in the porcine endometrium was described by Lord et al.

• Under some pathological conditions AT R internalization

  2023-08-04

  

  Under some pathological conditions, AT1R internalization is decreased when agonist exposure is prolonged. This weakens or removes the AT1R desensitization effect and leads to AT1R and downstream signal overactivation. AT1R overactivation can result in continued biological effects such as sustained v

• Structural and functional imaging studies searching for spec

  2023-08-04

  

  Structural and functional imaging studies searching for specific cortical areas related to each cognitive function domain have provided clues to the spreading patterns of cognitive dysfunction (Domoto-Reilly et al., 2012, Firbank et al., 2016, Li et al., 2012, Machulda et al., 2003, Mandal et al., 2

• br The lipoxygenase pathway in diseases of the nervous syste

  2023-08-04

  

  The 12/15-lipoxygenase pathway in diseases of the nervous system Conclusions and future perspectives Arachidonic SC75741 and other polyunsaturated fatty acids, and their lipid metabolites, play very important roles in human health and disease. This review has outlined the functions of 12- and

• Previous studies to investigate the functions of AHR

  2023-08-04

  

  Previous studies to investigate the functions of AHR in Treg (-)-epicatechin mg have employed a loss-of-function approach, using AHR complete-null mice, or a gain-of-function approach by ligand administration. However, these approaches may confound the interpretation of the results. For example, th

• br Materials and methods br Results br

  2023-08-04

  

  Materials and methods Results Discussion Conclusions These studies provide important mechanistic insights to explain the long-established physiological observation that obese adipose tissue has higher rates of basal lipolysis. Increased lipolysis contributes to increased hepatic p 00 rec

• Whereas more research is needed to identify the precise

  2023-08-03

  

  Whereas more research is needed to identify the precise mechanism by which FIN exerts its antidyskinetic effect, the rho kinase inhibitors that it can negatively modulate dopaminergic transmission is also supported by our previous findings. Indeed, we have previously shown that FIN completely revers

• br Results br Discussion br Conclusion The flux of

  2023-08-03

  

  Results Discussion Conclusion The flux of glucose into cytosolic short chain acyl-CoAs was maintained in pure beta angiotensin 2 receptor blocker in the presence of inhibition of ATP citrate lyase with hydroxycitrate and also in a cell line with >90% ATP citrate lyase knockdown suggesting

• br Materials and methods br Results Dried leaves used

  2023-08-03

  

  Materials and methods Results Dried SCF, murine recombinant protein sale used were 48.46 g C. benghalensis, 857.98 g T. zebrina and 25.09 g T. fluminensis. The samples gave 12.9% C. benghalensis, 0.078% T. zebrina and 3.06% T. fluminensis methanol extracts. The methanol extracts were evaluat

• br Materials and methods br

  2023-08-03

  

  Materials and methods Results RT-PCR showed that both arginase 1 and 2 were expressed in the OB of Korean roe deer (Fig. 1). Immunoblotting detected arginase 1 in the OB of roe deer (Fig. 2A, left lane) at a molecular weight of approximately 37kDa, which is the size of the enzyme in the rat O

• Serum concentrations of APP and antioxidants of the queens

  2023-08-03

  

  Serum concentrations of APP and antioxidants of the 10 queens with pyometra before surgery (T0), at day two (T1) and at day 10 (T2) after ovariohysterectomy are presented in Fig. 1. Concentrations of SAA and Hp were significantly lower (P  Discussion Acute phase protein responses were already desc

15560 records 277/1038 page Previous Next First page 上5页 276277278279280 下5页 Last page