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Milrinone In conclusion our results show that P C enhances
2021-11-08

In conclusion, our results show that P7C3 enhances endogenous neurogenesis by upregulating the generation of endogenous neuroblasts and neural stem/progenitor cells by increasing the expression of neuroprotective proteins (Bcl-2, ki67, DCX, adam11, adamts20, and β-tub3) by activation of the cAMP/PKA
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Although it is currently unknown why
2021-11-08

Although it is currently unknown why the longer splice variant found in the human has not been found in any other species, similar results have been reported for other receptors, including the p2y inhibitor receptor splice variant ERbeta2 identified in human and primate, but not other species (Sier
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The global spread and ever
2021-11-08

The global spread and ever-increasing incidence of metabolic syndrome over the past few decades has not only categorized it as an ‘epidemic’ but has also dramatically increased the risk of cardiovascular diseases and diabetes. The increase in prevalence of diabetes in the United States alone has bee
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Entry into CNS is tightly regulated by highly dynamic barrie
2021-11-08

Entry into CNS is tightly regulated by highly dynamic barriers, namely, the BBB, the blood-CSF barrier, and the arachnoid epithelium (Abbott et al., 2010; Yasuda et al., 2013). Similar barriers also exist within the CNS including the ependymal barrier as well as the cellular membrane barriers of the
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There is a dual inducer of both galanin and
2021-11-08

There is a dual inducer of both galanin and super-threshold pain. First, injury-induced pain may stimulate galanin secretion. After peripheral nerve injury, the galanin expression level was upregulated in dorsal root ganglion (DRG), dorsal horn and hypothalamic arcuate of rats [25], [28], [33]. The
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br Material and methods br Results
2021-11-08

Material and methods Results Discussion It is challenging to discriminate between HIV monoinfection and HIV-1/2 dual infection in settings where both viruses co-exist, due to cross-reactivity in serological tests. Thus, the gold standard for detection of HIV-1/2 dual infection is through NA
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br Introduction Verticillium dahliae Kleb is a soil
2021-11-06

Introduction Verticillium dahliae (Kleb.) is a soil-borne fungal pathogen that is able to infect hundreds of plant species, and causes vascular wilt disease [1], [2]. In nature, the infection of V. dahliae initiates from the germination of resting structures called microsclerotia [3]. The germina
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In conclusi http www apexbt com media diy images
2021-11-06

In conclusion, Glu transactions in glia cells are mediated through Glu receptors and transporters. From a biochemical perspective, the specificity of the cascades has started to be elucidated. A model of our present findings is depicted in Fig. 6. Acknowledgements This work was supported by Gran
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ICH induced striatal lesion produced a
2021-11-06

ICH-induced striatal lesion produced a reduction of EAAT1 expression analogous to the decreased glutamate uptake at 6 h. The combined reduction of excitatory amino monensin transporters and of glutamate uptake activity might explain the well-known glutamate excitotoxicity following brain ischemia (R
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The orientation of the immobilized enzyme may affect
2021-11-06

The orientation of the immobilized enzyme may affect its activity and stability and therefore the final biocatalyst performance. Since proteins present areas more prone to unfolding in their surface or near to it [36], the immobilization through these areas may improve the final biocatalyst stabilit
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br Materials and methods br Results and
2021-11-06

Materials and methods Results and discussion In order to identify genes required for photoautotrophic growth, we screened a random insertion mutant library of Synechocystis 6803 and obtained many mutants with impaired photoautotrophic growth. About 6000 random insertion colonies of the mutant
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Our results are consistent with the hypothesis that reduced
2021-11-06

Our results are consistent with the hypothesis that reduced Fas-mediated apoptosis in maternally activated T-lymphocytes could result in insufficient trophoblast invasion of the spiral rxr receptor as the activated T-lymphocytes become able to enhance the destruction of the cytotrophoblasts. A reduc
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In various models histamine has been shown to induce chemota
2021-11-06

In various models, histamine has been shown to induce chemotaxis. This was first appreciated over 40 years’ ago in studies with eosinophils (Clark et al., 1977). At that time, only histamine H1 and histamine H2 receptors were recognized and studies with ligands to these receptors indicated that neit
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Furthermore the role of GSK in the pathogenesis
2021-11-05

Furthermore, the role of GSK-3 in the pathogenesis of inflammation has been widely documented as it accompanies inflammatory conditions such as diabetes mellitus, mood disorders, Alzheimer’s disease, cancer (Jope et al., 2007), and has been associated with atherothrombotic CVD events. However, anoth
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A motivation for this study is the ability
2021-11-05

A motivation for this study is the ability of PGD2 to inhibit hair lengthening (). Here we demonstrate that PGD2 also inhibits hair regeneration after wounding. Thus, PGD2 and Gpr44 inhibition of the hair follicle occurs in multiple contexts and may be exploited in future therapies. Pharmaceutical c
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