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The study looking at the recovery of
2020-08-03
The study looking at the recovery of cellular material showed that there was a higher percentage of recovery of DNA as a result of swabbing a non-stained fingermark than when applying DD to the fingermark and then collecting with a swab. DD, which is an external binder, binds to the sugar phosphate
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br Materials and methods br
2020-08-03
Materials and methods Results Discussion In this report, the influence of the ung, dug, and dut genes in preventing uracil residues from accumulating in E. coli DNA was quantitatively determined using a novel assay, the Ung-ARP assay. We found that inactivation of the ung gene in CY10 resul
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An interesting feature of most if not all the Pro
2020-08-01
An interesting feature of most, if not all the Pro residues in the Yaa position of mammalian collagens is that they are modified to 4-hydroxyproline (Hyp) residues. This occurs during intracellular biosynthesis, prior to the three individual chains folding to give a triple helical structure [3]. Thi
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br Disclosure statement br Acknowledgment and sources
2020-08-01
Disclosure statement Acknowledgment and sources of funding We would like to thank Dr. Brain Lau, who helped us strongly with the editing and reviewing of the manuscript. The research was funded by the Joint Council Office (JCO), Agency for Science, Technology & Research (A*STAR), Singapore.
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br Introduction Epithelial mesenchymal transition EMT is a b
2020-07-31
Introduction Epithelial-mesenchymal transition (EMT) is a biological process by which epithelial RWJ 56110 lose cell polarity and cell-cell adhesion, and gain mesenchymal features with an increase of migratory and invasive properties [1]. EMT is essential for mesoderm formation during embryo deve
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br Acknowledgements We thank Dr Xiaochao Ma in the School
2020-07-31
Acknowledgements We thank Dr. Xiaochao Ma in the School of Pharmacy at the University of Pittsburgh, who kindly provided us the liver of wild type and Cyp3a-null mice. Introduction Cytochrome P450 jlk play major roles in the metabolism of endogenous compounds and biotransformation of xenobio
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Assays in vitro and in
2020-07-31
Assays in vitro and in vivo suggest that LRSAM1 likely assembles into oligomers. More importantly, the self-association may contribute to the intermolecular ubiquitination and provides a method to test ubiquitination sites. Site-specific auto-ubiquitination of E3 ligase is one of the critical mediat
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E is a classical initiator protein and as such plays
2020-07-31
E1 is a classical initiator protein and, as such, plays several roles in the initiation and catalysis of viral DNA synthesis. E1 must first recognize a specific segment of the viral Donitriptan hydrochloride known as the “origin of DNA replication”, or “ori” for short. For most PV types examined to
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Tamoxifen is included in the
2020-07-31
Tamoxifen is included in the treatment protocol of ER+ breast carcinoma patients routinely. Although tamoxifen improves patients\' survival, unfortunately a large number of ER+ patients don\'t response to tamoxifen treatment (Yager and Davidson, 2006). Detection of molecular markers which could take
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br Materials and methods The three pieces
2020-07-31
Materials and methods The three pieces of cotton fabric were submitted to the analysis: evidence no. 1 was a white handkerchief with visible yellow stiff stains and lacerations perhaps related to multiple cuts for old sampling; evidence no. 2 was a piece of white and green cotton fabric showing b
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br Conclusion br Acknowledgment The authors would like to th
2020-07-30
Conclusion Acknowledgment The authors would like to thank “Science and Engineering Research Board (SERB) of Department of Science and Technology (DST) Govt. of India” (Grant No.YSS/2015/002017) for funding the project. Introduction Mutations occurring within EGFR exons 18 to 21 are present
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To evaluate the new quadrupolar CPA qCPA the pure fluid
2020-07-30
To evaluate the new quadrupolar CPA (qCPA) the pure fluid properties of CO2 are predicted both in the critical region and in the compressed liquid region. The model is furthermore applied for the prediction and correlation of binary mixtures with CO2 and n-alkanes, water, alcohols and a few quadrupo
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Enasidenib br Results and discussion First the
2020-07-30
Results and discussion First, the results for n-pentane diluted and propane diluted bitumen with CPA-C5 and CPA-C3 characterization approaches are discussed and compared. Then, the extension of the model to other bitumens and solvents is examined. Finally, the limiting number of pseudo-components
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br Materials and methods br Results and
2020-07-30
Materials and methods Results and discussion Concluding remarks The successful knockout of the tpi1 gene in K. pneumoniae DSM2026 and the physiological study of mutants grown on different carbon sources led to the discovery of a novel tpi2 gene in this bacterium. The direct enzyme assay and
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The CRM protein is encoded by the XPO
2020-07-29
The CRM1 protein is encoded by the XPO1 gene and was originally identified by a genetic screen of S. pombe that revealed involvement of the protein in control of chromosomal structure (Adachi & Yanagida, 1989). CRM1 was later characterized and designated as a ubiquitous nuclear export receptor prote
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