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Gene amplification PCR amplifications were performed using g
2019-09-25
Gene amplification. PCR amplifications were performed using genomic DNA from the different organisms studied as template and two degenerate oligonucleotides (PP1 and PP2) as primersPP1 corresponded to the sense codons of the amino ARCA EGFP motif AGGI(A/S)EM, and PP2 to the antisense sequence of th
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Electroencephalographs at onset ranged from hypsarrhythmia
2019-09-25
Electroencephalographs at onset ranged from hypsarrhythmia to mild abnormalities but more abnormalities in background rhythms and epileptiform activity develop over time.15, 17, 19, 48, 52, 54, 55 Early mild abnormalities that sometimes precede a diffuse encephalopathy included focal delta slowing i
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br torsion is a urological emergency that may
2019-09-25
torsion is a urological emergency that may occur at any age. To establish blood flow surgical detorsion is required in most cases while detorsion can sometimes be achieved by hand assistance. Regardless of the correction method 2 phases (I/R) negatively affect germ cells. The torsion phase decreas
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5-BrdU The N B method has the overall advantage that
2019-09-25
The N&B method has the overall advantage that it is not restricted to certain dyes specific for energy transfer [55], and is also able to detect higher order receptor 5-BrdU on the focal point in living cells. Conclusion The N&B method has shown to be a powerful tool to locate and quantify the
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br Acknowledgements The authors thank Drs C Klein
2019-09-25
Acknowledgements The authors thank Drs. C. Klein, I. Canisso and A. Claes with assistance in obtaining tissues. Supported by the Albert G. Clay Endowment, University of Kentucky. Introduction Neoplastic cells often develop drug resistance during tumor progression or cancer treatment (Turner a
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In rodents Wang et al Wang and Tsirka
2019-09-25
In rodents (Wang et al., 2003, Wang and Tsirka, 2005b, Zhu et al., 2012) and humans (Wang et al., 2011), the major forms of cell death after ICH are necrosis and apoptosis. In the perihematomal region of rodents, the number of necrotic and apoptotic cells peaks at 72h post-ICH (Matsushita et al., 20
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br Acknowledgements br Introduction Endothelial cells consti
2019-09-25
Acknowledgements Introduction Endothelial Spadin constitute a unique source of humoral factors that may regulate the functions of other cell types via paracrine or endocrine pathways [1]. Among the many molecules originated from the endothelium, nitric oxide (NO) plays versatile roles in maint
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From these and other studies it is clear that acriflavine
2019-09-25
From these and other studies, it is clear that acriflavine is an interesting dorsomorphin with pleiotropic anticancer effects [21], [22], [43]. Its past systemic use in the clinical setting as an antibiotic without any major toxicity reported encourages further development of the drug for cancer tre
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Expression of EBI and its function
2019-09-25
Expression of EBI2 and its function for migration in vitro in T cells was recently reported (Chalmin et al., 2015, Hannedouche et al., 2011, Liu et al., 2011, Pereira et al., 2009). Pereira et al. (2009) used an EBI2 reporter mouse and found that most CD4+ T cells, but only approximately half of the
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The genetic asymmetries between parental genomes are also th
2019-09-24
The genetic asymmetries between parental genomes are also the subject of genetic conflict theory. This concept proposes that paternally inherited imprinted genes “extract” nutrients from the mother during gestation. By contrast, maternally inherited genes counteract the effect of paternal genes (Con
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br Disclosures br Acknowledgements This work
2019-09-24
Disclosures Acknowledgements This work was supported by the Natural Science Foundation of China (No. 81560587); the Fok Ying-Tong Education Foundation of China (No. 151107), the basic ability promotion project for young and middle-aged teachers in Universities in Guangxi (No. 2018KY1146) and t
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br Are incretins the only
2019-09-24
Are incretins the only mediators of the anti-hyperglycaemic effects of DPP-4 inhibitors? Even though both GLP-1 and GIP were identified as substrates for DPP-4 early on [17], [19], [20], [22], and DPP-4 inhibition in vivo raises levels of the intact endogenous forms of both of them [43], [44], fr
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In many studies spatial and
2019-09-24
In many studies, spatial and temporal expression and subcellular localizations of the DNMTs are examined in greater detail. These studies are evaluated and discussed in the remaining part of the article. DNMT1 protein expression was characterized in the genital ridge of the primitive mouse gonad at
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Finally this study described that the lead compound acted
2019-09-24
Finally, this study described that the lead AZD 3965 (1) acted as an efficient alkylating agent for the G4 structure in addition to the previously reported T-T mismatch structure. The shortcoming of probe (1) is the lack of a structure selectivity, but that can be overcome by changing the acridine
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br Experimental Procedures br Acknowledgments br
2019-09-24
Experimental Procedures Acknowledgments Introduction Incessant consumption of fossil fuels brings on global energy crisis and serious environmental concerns. Hence, the researchers have paid considerable attention to alternative renewable bioenergy. Microalgae has been considered as potenti
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